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Abubuwan haɗarin da ke faruwa ga COVID-19 sun haɗa da shekaru, jinsi, hauhawar jini, ciwon sukari da kiba. Kwanan nan, wasu shaidun asibiti da karatu sun ba da shawarar yiwuwar haɗuwa tsakanin PCOS da COVID-19.
Nazarin ya ce matan da ke fama da cututtukan ƙwayoyin cuta na polycystic ovaries (PCOS) ko polycystic ovarian disease (PCOD) na iya kasancewa cikin haɗarin kamuwa da cutar COVID-19 idan aka kwatanta da mata ba tare da PCOS ba. Wannan labarin zai tattauna yadda kuma me yasa hakan zai yiwu. Karanta don ƙarin sani.
COVID-19 Da Mata Masu Fama Daga PCOS
Dangane da binciken da aka buga a mujallar Turai ta Endocrinology, matan da ke dauke da cutar ta PCOS suna cikin kasada 28 cikin 100 na kamuwa da cutar ta COVID-19 idan aka kwatanta da mata ba tare da yanayin ba. An kirga sakamakon bayan daidaita shekarun, BMI da haɗarin haɗari. [1]
Ba tare da gyare-gyaren da aka ambata ba, binciken ya nuna cewa matan PCOS suna cikin 51 kashi mafi haɗarin COVID-19 tsakanin mata ba tare da PCOS ba.
Me yasa Marasa lafiya na PCOS ke cikin Risarin Hadarin COVID-19?
Ya zuwa yau, COVID-19 ya shafi kusan mutane miliyan 124 a duk duniya, tare da mutane miliyan 70.1 da aka gano da kuma mutane miliyan 2.72 da suka mutu. Yawancin binciken da aka buga sun nuna cewa an tabbatar da cutar COVID-19 a dakin gwaje-gwaje sun fi yawa ga maza a kasashe da yawa idan aka kwatanta da mata.
Kodayake dalilin yana da yawa, tasirin hormone androgen ana ɗauka ɗayan manyan dalilai ne na bambancin bambancin jinsi a cikin kamuwa da cuta.
Androgen yawanci ana kiran sa azaman hormone na namiji wanda ke jagorantar ci gaba da kiyaye halayen maza da ayyukansu na haihuwa. [biyu]
Hakanan, hormone yana cikin maza da mata, amma babban aikinsa shine haɓaka testosterone da haɓaka, biyu daga cikin homonin jima'i na maza da yawa.
PCOS cuta ce ta endocrine wanda matakan androgens (hormone maza) ke ƙaruwa, maimakon estrogen (hormone mace). Wannan yana haifar da hauhawar jini da kuma lalatawar kwayayen, yana haifar da rashin haihuwa a wasu ba tare da ingantaccen bincike da magani ba.
Kamar yadda ake ɗauke da sinadarin asrogen shine babban mahimmin haɗarin kamuwa da cutar COVID-19, ana iya cewa matan PCOS na iya zama masu saurin kamuwa da cutar, la'akari da cewa wasu dalilai kamar su kiba a cikin matan PCOS suma na iya zama dalilin.
Sauran Dalilai
1. Juriya na insulin
PCOS tana da alaƙa da cututtukan rayuwa kamar ƙarfin insulin da ciwon sukari. Insulin wani hormone ne wanda ke taimakawa sarrafa matakan glucose a jiki, tare da sarrafa metabolism na sunadarai da lipids.
Rashin ƙarfin insulin yana haɓaka lokacin da jiki bai amsa insulin ba, yana haifar da rashin amfani da glucose cikin jini don kuzari, wanda ke haifar da ƙara yawan glucose na jini. Yawan glucose ya fara katsalandan tare da ƙwayoyin garkuwar jiki kamar ƙwayoyin B, macrophages da ƙwayoyin T, wanda ke haifar da raguwar ayyukan garkuwar jiki.
Rashin aiki na tsarin rigakafi saboda juriya na insulin, wanda ya fara saboda PCOS na iya ƙarshe faɗin dalilin da ya sa mata da PCOS ke fama da cutar coronavirus ƙwarai. [3]
2. Kiba
Wani bincike ya nuna cewa jim kadan bayan fitowar kwayar cutar kankara, a tsakanin mutanen da suka sha iska, rabon marasa lafiyar masu kiba ya yi yawa, sai kuma yawan mace-mace tsakanin wadannan mutane. [4]
Wani binciken ya kuma nuna gaskiyar cewa yayin annobar da ta gabata ta kamuwa da H1N1 ko mura, alaƙar yanayin ta kasance babba ga masu kiba. [5]
yadda ake girma farce cikin sauri
Kimanin kashi 38-88 na mata masu cutar PCOS an same su da kiba ko kiba. Abubuwan haɗin da ke tsakanin kiba, PCOS da COVID-19 na iya kammalawa, cewa matan PCOS sun fi saukin kamuwa da COVID-19 saboda ƙiba ko kiba.
3. Rashin Vitamin D
Rashin haɗin Vitamin D yana da alaƙa da cutar PCOS da COVID-19 ta hanyoyi da yawa. Vitamin D muhimmin bitamin ne wanda zai iya taimakawa hana kamuwa da cututtukan numfashi na COVID-19 ta hanyar haɓakar haɓaka-kariya da rage cytokines mai kumburi da ke haifar da ciwon huhu.
A cikin kusan kashi 67-85 na mata masu cutar PCOS, an lura da babban rashi na bitamin D. [6]
Rashin bitamin D na iya haifar da lalacewar garkuwar jiki, ƙara cytokines mai kumburi da haɗarin kamuwa da cututtuka kamar ciwon sukari, juriya na insulin da kiba, duk rikitarwa ga PCOS.
Saboda haka, ana iya cewa rashi bitamin D zai iya haɗuwa da PCOS da haɓaka rikitarwa da ƙimar mutuwa saboda COVID-19.
4. Kyakkyawan microbiota
Gut dysbiosis ko dysfunction na gut microbiota yana da alaƙa da yanayin kiwon lafiya kamar PCOS.
PCOS da lafiyar gut suna tafiya hannu da hannu. Mata da PCOS galibi ana samun su da gut dysbiosis. Koyaya, idan ana gudanar da matakan sukari da kyau kuma ana kula da tsarin narkewa a cikin PCOS, za'a iya inganta lafiyar gut.
Canzawa a cikin abun da ke cikin kwayar halittar microbiome na iya shafar tsarin garkuwar jiki, tsarin farko na jiki wanda ke kare mu daga kamuwa da cuta kuma don haka, ya sa mu kamu da cututtuka kamar COVID-19.
Yin amfani da maganin rigakafi don kiyaye daidaitaccen ƙwayar microbiota na hanji na iya taimakawa haɓaka rigakafi da hana haɗarin COVID-19.
Don Kammalawa
Juriya na insulin na iya haɓaka samar da androgens a cikin mata tare da PCOS. Kiba da kiba na iya lalata juriya na insulin don haka, haɓaka haɓakar inrogene. Wannan na iya haifar da lalacewar tsarin na rigakafi saboda layin endocrine-immunity, wanda hakan zai iya haifar da barazanar COVID-19 a cikin matan PCOS.
